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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BECN1
All Species:
36.36
Human Site:
T406
Identified Species:
53.33
UniProt:
Q14457
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14457
NP_003757.1
450
51896
T406
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Chimpanzee
Pan troglodytes
XP_511522
450
51866
T406
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Rhesus Macaque
Macaca mulatta
XP_001111932
450
51890
T406
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Dog
Lupus familis
XP_537634
362
42279
G319
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
O88597
448
51515
T404
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Rat
Rattus norvegicus
Q91XJ1
448
51538
T404
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514527
394
45783
T350
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Chicken
Gallus gallus
Q5ZKS6
447
51416
T403
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Frog
Xenopus laevis
Q6GP52
445
51275
T401
D
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Zebra Danio
Brachydanio rerio
P13104
284
32704
F241
E
A
E
T
R
A
E
F
A
E
R
S
V
A
K
Tiger Blowfish
Takifugu rubipres
NP_001032963
447
51199
T403
E
K
G
K
I
E
D
T
G
G
S
G
G
S
Y
Fruit Fly
Dros. melanogaster
Q9VCE1
422
48852
D378
M
E
K
G
K
I
I
D
P
S
T
G
N
S
Y
Honey Bee
Apis mellifera
XP_392365
430
49618
D382
M
D
R
G
K
I
E
D
S
A
T
G
N
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786368
415
47747
D372
M
T
N
G
K
L
E
D
T
A
A
G
Q
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M367
517
58486
E439
L
N
L
P
Y
K
I
E
K
D
K
V
L
G
Y
Baker's Yeast
Sacchar. cerevisiae
Q02948
557
63242
K496
E
L
P
Y
I
M
N
K
D
K
I
N
G
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
78.8
N.A.
97.3
97.3
N.A.
76.8
91.7
88.6
20
81.1
49.1
56.4
N.A.
57.5
Protein Similarity:
100
99.7
99.7
79.5
N.A.
98
98.2
N.A.
81.5
94.6
94.8
36.4
89.5
67.7
69.3
N.A.
71.5
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
93.3
6.6
100
20
20
N.A.
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
100
100
100
20
100
33.3
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
0
7
13
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
7
57
19
7
7
0
0
0
0
0
% D
% Glu:
63
7
7
0
7
57
19
7
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
7
57
19
0
0
0
7
63
57
7
82
63
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
63
13
13
0
0
0
7
0
0
0
0
% I
% Lys:
7
57
13
57
19
7
0
7
7
7
7
0
0
0
7
% K
% Leu:
7
7
7
0
0
7
0
0
0
0
0
0
7
7
0
% L
% Met:
19
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
0
7
0
0
0
0
7
13
0
0
% N
% Pro:
0
0
7
7
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
7
0
7
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
7
13
57
7
7
69
13
% S
% Thr:
0
7
0
7
0
0
7
57
7
0
13
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
0
0
0
0
0
0
7
82
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _